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ZIRC
ZFIN ID: ZDB-GENE-050522-545
Gene Name: diphthamide biosynthesis 3
Gene Symbol: dph3    Nomenclature History

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Previous Name: zgc:112231

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and tRNA wobble uridine modification. Predicted to localize to the cytosol and nucleus. Orthologous to several human genes including DPH3 (diphthamide biosynthesis 3).
Genome Resources: Alliance (1),  Gene:553692 (1),  Ensembl(GRCz11):ENSDARG00000043360 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30624 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dph3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dph3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peptidyl-diphthamide biosynthetic process from peptidyl-histidine (more)
    Cellular Component cytosol (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007872 (1)
  • InterPro:IPR036671 (1)
  • PROSITE:PS51074 (1)
  • Pfam:PF05207 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dph3-201 (1)    Ensembl 555
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dph3 No data available
    MARKER RELATIONSHIPS
    dph3 Contained in: [BAC] CH211-147G19 (1) (order this)
    dph3 Encodes: [cDNA] MGC:112231 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001159824 (1)
    Genomic GenBank:CR936426 (1) 158934 bp
    Select Tool
    Polypeptide UniProtKB:Q502H4 (1) 85 aa
    Sequence Clusters UniGene:90599 (1)
    Sequence Information (all 11)
    ORTHOLOGY for dph3 ( Chr: 6 )
    CITATIONS (14)