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Gene

uqcrb

ID
ZDB-GENE-050522-542
Name
ubiquinol-cytochrome c reductase binding protein
Symbol
uqcrb Nomenclature History
Previous Names
  • im:6900881
  • zgc:109893
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Acts upstream of or within angiogenesis. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. Is expressed in several structures, including adaxial cell; alar plate midbrain region; digestive system; optic tectum; and pronephric duct. Human ortholog(s) of this gene implicated in inherited metabolic disorder and mitochondrial complex III deficiency nuclear type 3. Orthologous to human UQCRB (ubiquinol-cytochrome c reductase binding protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Cho et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With uqcrb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitochondrial complex III deficiency nuclear type 3 Alliance Mitochondrial complex III deficiency, nuclear type 3 615158
Associated With uqcrb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR003197 Cytochrome b-c1 complex subunit 7
Homologous_superfamily IPR036544 Cytochrome b-c1 complex subunit 7 superfamily
Domain Details Per Protein
Protein Length Cytochrome b-c1 complex subunit 7 Cytochrome b-c1 complex subunit 7 superfamily
UniProtKB:Q4VBV1 111
UniProtKB:I3IS20 79
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations