Gene
uqcrb
- ID
- ZDB-GENE-050522-542
- Name
- ubiquinol-cytochrome c reductase binding protein
- Symbol
- uqcrb Nomenclature History
- Previous Names
-
- im:6900881
- zgc:109893
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Involved in angiogenesis. Predicted to localize to mitochondrial respiratory chain complex III. Is expressed in several structures, including adaxial cell; alar plate midbrain region; digestive system; optic tectum; and pronephric duct. Human ortholog(s) of this gene implicated in inherited metabolic disorder and mitochondrial complex III deficiency nuclear type 3. Orthologous to human UQCRB (ubiquinol-cytochrome c reductase binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6900881 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Cho et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex III deficiency nuclear type 3 | Alliance | Mitochondrial complex III deficiency, nuclear type 3 | 615158 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome b-c1 complex subunit 7 | Cytochrome b-c1 complex subunit 7 superfamily |
|---|---|---|---|
|
UniProtKB:Q4VBV1
|
111 |
Interactions and Pathways
No data available
Plasmids
No data available