ZFIN ID: ZDB-GENE-050522-500
Gene Name: eukaryotic translation elongation factor 2a, tandem duplicate 1
Gene Symbol: eef2a.1    Nomenclature History

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Previous Names: si:dkey-110c1.3, zgc:113191

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have GTPase activity; ribosome binding activity; and translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to localize to cytosol and ribonucleoprotein complex. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Orthologous to human EEF2 (eukaryotic translation elongation factor 2).
Genome Resources: Alliance (1),  Gene:792182 (1),  Ensembl(GRCz11):ENSDARG00000042094 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7162545]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa29761 Point Mutation Unknown Splice Site ENU
sa29762 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH eef2a.1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia type 26 Alliance ?Spinocerebellar ataxia 26 609306
DISEASE ASSOCIATED WITH eef2a.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process translation (more)
Cellular Component ribonucleoprotein complex (more)
Molecular Function GTPase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA eef2a.1-201 (1)    Ensembl 3825
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM eef2a.1 No data available
MARKER RELATIONSHIPS
eef2a.1 Contained in: [BAC] DKEY-110C1 (1) (order this)
eef2a.1 Encodes: [EST] IMAGE:7162545 (1)
[cDNA] MGC:113191 (1), MGC:192616 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045161 (1) 3825 nt
Genomic GenBank:BX005203 (1) 214843 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q1LXT2 (1) 854 aa
Sequence Information (all 23)
ORTHOLOGY for eef2a.1 ( Chr: 22 )
CITATIONS (23)