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ZIRC
ZFIN ID: ZDB-GENE-050522-494
Gene Name: von Hippel-Lindau binding protein 1
Gene Symbol: vbp1    Nomenclature History

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Previous Names: im:7140038, zgc:110686

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have tubulin binding activity. Predicted to be involved in microtubule-based process and tubulin complex assembly. Predicted to localize to the cytoplasm; polysome; and prefoldin complex. Is expressed in alar plate midbrain region; immature eye; myotome; neural plate; and optic tectum. Orthologous to human VBP1 (VHL binding protein 1).
Genome Resources: Alliance (1),  Gene:553651 (1),  Ensembl(GRCz11):ENSDARG00000030241 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [IMAGE:7140038]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010399Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34056 Point Mutation Unknown Splice Site, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vbp1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vbp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein folding (more)
    Cellular Component prefoldin complex (more)
    Molecular Function tubulin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004127 (1)
  • InterPro:IPR009053 (1)
  • InterPro:IPR016655 (1)
  • Pfam:PF02996 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vbp1-201 (1)    Ensembl 2213
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vbp1 No data available
    MARKER RELATIONSHIPS
    vbp1 Contained in: [BAC] CH73-19M13 (1) (order this), CH211-200P22 (1) (order this)
    vbp1 Encodes: [EST] IMAGE:7140038 (1) (order this)
    [cDNA] MGC:110686 (1) (order this)
    vbp1 Has Artifact: [EST] fk32f06
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020624 (1) 1078 bp
    Genomic GenBank:AL954129 (1) 161275 bp
    Select Tool
    Polypeptide UniProtKB:Q503D5 (1) 195 aa
    Sequence Clusters UniGene:76087 (1)
    Sequence Information (all 11)
    ORTHOLOGY for vbp1 ( Chr: 7 )
    CITATIONS (23)