ZFIN ID: ZDB-GENE-050522-482
Gene Name: phosphorylase, glycogen, muscle A
Gene Symbol: pygma    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: im:7150327, zgc:110706

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have glycogen phosphorylase activity and pyridoxal phosphate binding activity. Predicted to be involved in glycogen catabolic process. Predicted to localize to cytoplasm. Is expressed in several structures, including adaxial cell; eye; heart; integument; and musculature system. Human ortholog(s) of this gene implicated in glycogen storage disease V. Orthologous to human PYGM (glycogen phosphorylase, muscle associated).
Genome Resources: Alliance (1),  Gene:553655 (1),  Ensembl(GRCz11):ENSDARG00000055518 (1)
GENE EXPRESSION
All Expression Data: 13 figures from 2 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [IMAGE:7150327]
  6 figures (9 images) from Thisse et al., 2004 [IMAGE:7156459]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31059 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39334 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pygma N/A 1
    MO2-pygma N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pygma HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    glycogen storage disease V Alliance McArdle disease 232600
    DISEASE ASSOCIATED WITH pygma VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carbohydrate metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function 1,4-alpha-oligoglucan phosphorylase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pygma-201 (1)    Ensembl 2735
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pygma No data available
    MARKER RELATIONSHIPS
    pygma Contained in: [BAC] CH211-247J24
    pygma Encodes: [EST] IMAGE:7150327 (1), IMAGE:7156459 (1)
    [cDNA] MGC:110706 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020628 (1) 2763 nt
    Genomic GenBank:CR376834 (1) 150120 nt
    Select Tool
    Polypeptide UniProtKB:Q503C7 (1) 842 aa
    Sequence Information (all 10)
    ORTHOLOGY for pygma ( Chr: 21 )
    CITATIONS (25)