Gene

rgrb

ID
ZDB-GENE-050522-447
Name
retinal G protein coupled receptor b
Symbol
rgrb Nomenclature History
Previous Names
  • rgr2 (1)
  • wu:fb64c10
  • zgc:109930
  • zgc:92677
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; phototransduction; and visual perception. Predicted to be located in membrane. Is expressed in several structures, including digestive system; endocrine system; optic vesicle; visual system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 44. Orthologous to human RGR (retinal G protein coupled receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rgrb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 44 Alliance Retinitis pigmentosa 44 613769
Associated With rgrb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001793 Retinal pigment epithelium GPCR
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Retinal pigment epithelium GPCR
UniProtKB:A0A0G2KW99 290
UniProtKB:Q6DH22 291
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations