Gene

c9

ID
ZDB-GENE-050522-442
Name
complement component 9
Symbol
c9 Nomenclature History
Previous Names
  • wu:fb60b05
  • wu:fd50e04
  • zgc:112272
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Involved in cellular response to estrogen stimulus. Predicted to localize to membrane attack complex. Human ortholog(s) of this gene implicated in age related macular degeneration 15 and complement component 9 deficiency. Is expressed in liver and yolk syncytial layer. Orthologous to human C9 (complement C9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With c9 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
age related macular degeneration 15 Alliance {Macular degeneration, age-related, 15, susceptibility to} 615591
complement component 9 deficiency Alliance C9 deficiency 613825
Associated With c9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020863 Membrane attack complex component/perforin domain, conserved site
Domain IPR020864 Membrane attack complex component/perforin (MACPF) domain
Family IPR001862 Membrane attack complex component/perforin/complement C9
Family IPR037567 Complement component C9
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Length Complement component C9 LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A repeat Membrane attack complex component/perforin/complement C9 Membrane attack complex component/perforin domain, conserved site Membrane attack complex component/perforin (MACPF) domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:B8A565 673
UniProtKB:Q502F5 280
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations