ZFIN ID: ZDB-GENE-050522-442
Gene Name: complement component 9
Gene Symbol: c9    Nomenclature History

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Previous Names: wu:fb60b05, wu:fd50e04, zgc:112272

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Involved in cellular response to estrogen stimulus. Predicted to localize to membrane attack complex. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in age related macular degeneration 15 and complement component 9 deficiency. Orthologous to human C9 (complement C9).
Genome Resources: Alliance (1),  Gene:554141 (1),  Ensembl(GRCz11):ENSDARG00000016319 (2)
GENE EXPRESSION
All Expression Data: 18 figures from 5 publications
Directly Submitted Expression Data: 7 figures (5 images) from Thisse et al., 2004 [MGC:112272]
  5 figures (5 images) from Thisse et al., 2004 [IMAGE:7140385]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa598 Point Mutation Unknown Splice Site ENU
sa15017 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15909 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa33641 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH c9 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    age related macular degeneration 15 Alliance {Macular degeneration, age-related, 15, susceptibility to} 615591
    complement component 9 deficiency Alliance C9 deficiency 613825
    DISEASE ASSOCIATED WITH c9 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to estrogen stimulus (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA c9-201 (1)    Ensembl 2271
    ncRNA c9-002 (1)    Ensembl 588
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM c9 No data available
    MARKER RELATIONSHIPS
    c9 Contained in: [BAC] CH211-158M24 (1)
    c9 Encodes: [EST] fb60b05 (1), fd50e04 (1), fl31b09 (1), IMAGE:7140385 (1)
    [cDNA] MGC:112272 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001024435 (1) 1009 nt
    Genomic GenBank:BX510649 (1) 189844 nt
    Select Tool
    Polypeptide RefSeq:NP_001314855 (1)
    Sequence Information (all 16)
    ORTHOLOGY for c9 ( Chr: 5 )
    CITATIONS (30)