Gene

tdg.1

ID
ZDB-GENE-050522-44
Name
thymine DNA glycosylase, tandem duplicate 1
Symbol
tdg.1 Nomenclature History
Previous Names
  • tdg
  • wu:fb44b11
  • zgc:110622
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have pyrimidine-specific mismatch base pair DNA N-glycosylase activity and uracil DNA N-glycosylase activity. Predicted to be involved in base-excision repair, AP site formation. Predicted to localize to nucleus. Is expressed in retina. Orthologous to human TDG (thymine DNA glycosylase).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Manesia et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tdg.1 Human Ortholog
No data available
Associated With tdg.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005122 Uracil-DNA glycosylase-like
Family IPR015637 G/U mismatch-specific DNA glycosylase
Homologous_superfamily IPR036895 Uracil-DNA glycosylase-like domain superfamily
Domain Details Per Protein
Protein Length G/U mismatch-specific DNA glycosylase Uracil-DNA glycosylase-like Uracil-DNA glycosylase-like domain superfamily
UniProtKB:Q503G3 441
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations