ZFIN ID: ZDB-GENE-050522-431
Gene Name: endoplasmic reticulum to nucleus signaling 1
Gene Symbol: ern1
Sequence Ontology ID : SO:0000704

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Previous Names: sb:eu1005, zgc:109932

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity, protein kinase activity, and ribonuclease activity; involved in response to hypoxia; orthologous to human ERN1 (endoplasmic reticulum to nucleus signaling 1).
GENE EXPRESSION
All Expression Data: 6 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:109932]
  1 figure (1 image) from Thisse et al., 2005 [eu1005]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024314Tg Transgenic Insertion Unknown Unknown DNA
sa40179 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ern1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ern1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hypoxia (more)
    Molecular Function ATP binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR010513 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR011047 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR018391 (1)
  • InterPro:IPR018997 (1)
  • InterPro:IPR038357 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS51392 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF06479 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA ern1-002 (1) 344
    mRNA ern1-202 (1) 2996
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ern1 No data available
    MARKER RELATIONSHIPS
    ern1Contained in: [BAC] DKEY-188H10 (1) (order this)
    [Fosmid] CH1073-300I13 (1) (order this)
    ern1Encodes: [EST] eu1005 (1)
    [cDNA] MGC:109932 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020530 (1) 1128bp
    Genomic GenBank:CR392029 (1) 130871bp
    Select Tool
    Polypeptide UniProtKB:F1QYL2 (1) 1031aa
    Sequence Clusters UniGene:91817 (1)
    Sequence Information (all 14)
    OTHER ern1 GENE PAGES
  • Alliance (1)
  • Gene:553551 (1)
  • VEGA:OTTDARG00000027271 (1)
  • Ensembl(GRCz11):ENSDARG00000013997 (2)
  • ORTHOLOGY for ern1 (Chr: 3)
    CITATIONS (27)