ZFIN ID: ZDB-GENE-050522-424
Gene Name: ganglioside induced differentiation associated protein 1
Gene Symbol: gdap1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: si:rp71-1m12.2, zgc:112286

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to be involved in mitochondrial fission; mitochondrial fusion; and protein targeting to mitochondrion. Predicted to localize to integral component of mitochondrial outer membrane. Is expressed in central nervous system and cranial ganglion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease axonal type 2C; Charcot-Marie-Tooth disease axonal type 2K; Charcot-Marie-Tooth disease recessive intermediate A; and Charcot-Marie-Tooth disease type 4A. Orthologous to human GDAP1 (ganglioside induced differentiation associated protein 1).
Genome Resources: Alliance (1),  Gene:553702 (1),  Ensembl(GRCz11):ENSDARG00000058601 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:112286]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24464 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24465 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44107 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-gdap1 N/A 2
    DISEASE ASSOCIATED WITH gdap1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease axonal type 2K Alliance Charcot-Marie-Tooth disease, axonal, type 2K 607831
    Charcot-Marie-Tooth disease recessive intermediate A Alliance Charcot-Marie-Tooth disease, recessive intermediate, A 608340
    Charcot-Marie-Tooth disease type 4A Alliance Charcot-Marie-Tooth disease, type 4A 214400
    Charcot-Marie-Tooth disease, axonal, with vocal cord paresis 607706
    DISEASE ASSOCIATED WITH gdap1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuron projection development (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gdap1-201 (1)    Ensembl 1493
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gdap1 No data available
    MARKER RELATIONSHIPS
    gdap1 Contained in: [BAC] RP71-1M12
    gdap1 Encodes: [cDNA] MGC:112286 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020675 (1) 1511 nt
    Genomic GenBank:AL627168 (1) 180922 nt
    Select Tool
    Polypeptide UniProtKB:F1R9R0 (1) 372 aa
    Sequence Information (all 13)
    ORTHOLOGY for gdap1 ( Chr: 24 )
    CITATIONS (21)