ZFIN ID: ZDB-GENE-050522-417
Gene Name: homer scaffold protein 2
Gene Symbol: homer2    Nomenclature History

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Previous Names: zgc:111960, zmp:0000000677 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Involved in olfactory nerve formation and olfactory placode morphogenesis. Is expressed in musculature system; periderm; and somite. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Orthologous to human HOMER2 (homer scaffold protein 2).
Genome Resources: Alliance (1),  Gene:553661 (1),  Ensembl(GRCz11):ENSDARG00000059349 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:111960]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11712 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32179 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36549 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-homer2 N/A 1
    MO2-homer2 N/A 1
    MO3-homer2 N/A 1
    DISEASE ASSOCIATED WITH homer2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 68 Alliance ?Deafness, autosomal dominant 68 616707
    DISEASE ASSOCIATED WITH homer2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process olfactory nerve formation (more)
    Cellular Component cellular_component (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM homer2 No data available
    MARKER RELATIONSHIPS
    homer2 Encodes: [cDNA] MGC:111960 (1), MGC:175005 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020634 (1) 1474 nt
    Genomic GenBank:CABZ01090376 (1) 1329 nt
    Polypeptide UniProtKB:B0JZL8 (1) 350 aa
    Sequence Information (all 18)
    ORTHOLOGY for homer2 ( Chr: 18 )
    CITATIONS (18)