Gene

cfd

ID
ZDB-GENE-050522-411
Name
complement factor D (adipsin)
Symbol
cfd Nomenclature History
Previous Names
  • CFD (1)
  • cfdl (1)
  • fb61f12
  • wu:fb61f12
  • zgc:109940
  • zgc:92376
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in Notch signaling pathway; complement activation, alternative pathway; and proteolysis. Predicted to localize to extracellular space. Is expressed in adipose tissue; epidermis; periderm; pharyngeal arch; and pleuroperitoneal region. Orthologous to human CFD (complement factor D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cfd Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Complement factor D deficiency 613912
Associated With cfd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Domain IPR001254 Serine proteases, trypsin domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR037561 Complement factor D
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length Complement factor D Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site
UniProtKB:Q6DBS8 249
UniProtKB:A7MCG1 249
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations