ZFIN ID: ZDB-GENE-050522-396
Gene Name: thioredoxin related transmembrane protein 3a
Gene Symbol: tmx3a    Nomenclature History

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Previous Names: tmx3, txndc10, zgc:110025 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have thiol oxidase activity. Involved in eye development. Predicted to localize to cell surface and endoplasmic reticulum membrane. Is expressed in epiphysis; retina; and retinal photoreceptor layer. Orthologous to human TMX3 (thioredoxin related transmembrane protein 3).
Genome Resources: Alliance (1),  Gene:553578 (1),  Ensembl(GRCz11):ENSDARG00000038894 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (8 images) from Thisse et al., 2004 [MGC:110025]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028774Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9830 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11147 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19775 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39843 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tmx3a N/A 1
    MO2-tmx3a N/A 1
    PHENOTYPE
    Data: 2 figures from Chao et al., 2010
    Observed in:
    DISEASE ASSOCIATED WITH tmx3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tmx3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process eye development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function thiol oxidase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tmx3a-201 (1)    Ensembl 834
    tmx3a-203 (1)    Ensembl 1573
    ncRNA tmx3-003 (1)    Ensembl 842
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tmx3a No data available
    MARKER RELATIONSHIPS
    tmx3a Contained in: [BAC] DKEY-40I22 (1) (order this)
    tmx3a Encodes: [cDNA] MGC:110025 (1), MGC:191703 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020557 (1) 1511 nt
    Genomic GenBank:BX649522 (1) 155396 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QHZ9 (1) 438 aa
    Sequence Information (all 14)
    ORTHOLOGY for tmx3a ( Chr: 2 )
    CITATIONS (23)