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Gene

ndufa2

ID
ZDB-GENE-050522-377
Name
NADH:ubiquinone oxidoreductase subunit A2
Symbol
ndufa2 Nomenclature History
Previous Names
  • zgc:112340
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; intestinal bulb; musculature system; optic tectum; and optic vesicle. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 13. Orthologous to human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndufa2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 13 Alliance Mitochondrial complex I deficiency, nuclear type 13 618235
Associated With ndufa2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007741 Ribosomal protein/NADH dehydrogenase domain
Family IPR016464 NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 Ribosomal protein/NADH dehydrogenase domain Thioredoxin-like superfamily
UniProtKB:Q4VBI5 101
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations