Gene
ndufa2
- ID
- ZDB-GENE-050522-377
- Name
- NADH:ubiquinone oxidoreductase subunit A2
- Symbol
- ndufa2 Nomenclature History
- Previous Names
-
- zgc:112340
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to be involved in oxidation-reduction process. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Is expressed in several structures, including alar plate midbrain region; intestinal bulb; musculature system; optic tectum; and optic vesicle. Orthologous to human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112340 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 13 | Alliance | Mitochondrial complex I deficiency, nuclear type 13 | 618235 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 | Ribosomal protein/NADH dehydrogenase domain | Thioredoxin-like superfamily |
|---|---|---|---|---|
|
UniProtKB:Q4VBI5
|
101 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available