ZFIN ID: ZDB-GENE-050522-375
Gene Name: septin 3
Gene Symbol: sept3    Nomenclature History

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Previous Name: zgc:110051 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have GTPase activity and molecular adaptor activity. Predicted to be involved in cellular protein localization and cytoskeleton-dependent cytokinesis. Predicted to localize to cell division site; cytoskeleton; and neuron projection. Is expressed in nervous system and retina. Orthologous to human SEPTIN3 (septin 3).
Genome Resources: Alliance (1),  Gene:554123 (1),  Ensembl(GRCz11):ENSDARG00000030656 (2)
GENE EXPRESSION
All Expression Data: 14 figures from 3 publications
Directly Submitted Expression Data: 6 figures (14 images) from Thisse et al., 2004 [MGC:110051]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a327 Complex Unknown Unknown CRISPR
sa10682 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25647 Point Mutation Unknown Splice Site ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sept3 1
    CRISPR2-sept3 1
    CRISPR3-sept3 1
    CRISPR4-sept3 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sept3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sept3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular protein localization (more)
    Cellular Component presynapse (more)
    Molecular Function GTP binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sept3-201 (1)    Ensembl 2446
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sept3 No data available
    MARKER RELATIONSHIPS
    sept3 Contained in: [BAC] CH211-214C7 (1), DKEY-48A12 (1) (order this)
    sept3 Encodes: [cDNA] MGC:110051 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001024418 (1) 1303 nt
    Genomic GenBank:BX511120 (1) 204893 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A2BGU8 (1) 361 aa
    Sequence Information (all 12)
    ORTHOLOGY for sept3 ( Chr: 1 )
    CITATIONS (26)