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ZIRC
ZFIN ID: ZDB-GENE-050522-349
Gene Name: inositol(myo)-1(or 4)-monophosphatase 2
Gene Symbol: impa2    Nomenclature History

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Previous Name: zgc:110201

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol phosphate dephosphorylation and signal transduction. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Is expressed in brain; central nervous system; epiphysis; optic vesicle; and retina. Orthologous to human IMPA2 (inositol monophosphatase 2).
Genome Resources: Alliance (1),  Gene:553595 (1),  Ensembl(GRCz11):ENSDARG00000059411 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:110201]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24420 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25202 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH impa2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH impa2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inositol biosynthetic process (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 11)
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM impa2 No data available
    MARKER RELATIONSHIPS
    impa2 Encodes: [cDNA] MGC:110201 (1) (order this), MGC:192627 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020572 (1)
    Genomic GenBank:CABZ01114066 (1) 2051 bp
    Polypeptide UniProtKB:Q503S9 (1) 275 aa
    Sequence Clusters UniGene:45578 (1)
    Sequence Information (all 18)
    ORTHOLOGY for impa2 ( Chr: 24 )
    CITATIONS (17)