ZFIN ID: ZDB-GENE-050522-345
Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Gene Symbol: lamtor3    Nomenclature History

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Previous Names: mapksp1, zgc:110207

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in cellular protein localization; cellular response to amino acid stimulus; and positive regulation of TOR signaling. Predicted to localize to the Ragulator complex. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3).
Genome Resources: Alliance (1),  Gene:553597 (1),  Ensembl(GRCz11):ENSDARG00000057075 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110207]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38926 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lamtor3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lamtor3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular protein localization (more)
    Cellular Component Ragulator complex (more)
    Molecular Function CONTRIBUTES_TO   guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR015019 Ragulator complex protein LAMTOR3
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lamtor3-203 (1)    Ensembl 728
    ncRNA lamtor3-002 (1)    Ensembl 789
    lamtor3-003 (1)    Ensembl 578
    lamtor3-004 (1) 589
    lamtor3-005 (1)    Ensembl 536
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lamtor3 No data available
    MARKER RELATIONSHIPS
    lamtor3 Contained in: [BAC] DKEY-20I10 (1) (order this)
    lamtor3 Encodes: [cDNA] MGC:110207 (1), MGC:192102 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020574 (1) 713 bp
    Genomic GenBank:CT025771 (1) 190607 bp
    Select Tool
    Polypeptide UniProtKB:B8JJN5 (1) 138 aa
    Sequence Information (all 17)
    ORTHOLOGY for lamtor3 ( Chr: 13 )
    CITATIONS (20)