Gene

nle1

ID
ZDB-GENE-050522-321
Name
notchless homolog 1 (Drosophila)
Symbol
nle1 Nomenclature History
Previous Names
  • fc12b09
  • fc45f01
  • wu:fc12b09
  • wu:fc45f01
  • zgc:110281 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to be involved in Notch signaling pathway and ribosomal large subunit assembly. Predicted to localize to nucleolus. Is expressed in alar plate midbrain region; nervous system; optic vesicle; and pharyngeal arch. Orthologous to human NLE1 (notchless homolog 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nle1 Human Ortholog
No data available
Associated With nle1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR001632 G-protein, beta subunit
Domain IPR012972 NLE
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein, beta subunit G-protein beta WD-40 repeat NLE Quinoprotein alcohol dehydrogenase-like superfamily WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q503R2 476
UniProtKB:F1QDT3 476
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations