ZFIN ID: ZDB-GENE-050522-305
Gene Name: macrophage expressed 1, tandem duplicate 2
Gene Symbol: mpeg1.2    Nomenclature History

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Previous Name: zgc:110354

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Involved in defense response to bacterium. Predicted to localize to the integral component of membrane. Orthologous to human MPEG1 (macrophage expressed 1).
Genome Resources: Alliance (1),  Gene:553612 (1),  Ensembl(GRCz11):ENSDARG00000043093 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Benard et al., 2015
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21256 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34368 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mpeg1.2 N/A 1
    MO2-mpeg1.2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mpeg1.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mpeg1.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to bacterium (more)
    Cellular Component integral component of membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR020864 Membrane attack complex component/perforin (MACPF) domain
    Family IPR039707 Macrophage-expressed gene 1 protein
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mpeg1.2-201 (1)    Ensembl 2638
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mpeg1.2 No data available
    MARKER RELATIONSHIPS
    mpeg1.2 Contained in: [BAC] CH73-40N22 (1)
    mpeg1.2 Encodes: [cDNA] MGC:110354 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020586 (1) 2718 bp
    Genomic GenBank:CU984571 (1) 133450 bp
    Select Tool
    Polypeptide UniProtKB:A9C3Q1 (1) 713 aa
    Sequence Information (all 10)
    ORTHOLOGY for mpeg1.2 ( Chr: 8 )
    CITATIONS (22)