ZFIN ID: ZDB-GENE-050522-301
Gene Name: zinc finger, MYND-type containing 11
Gene Symbol: zmynd11    Nomenclature History

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Previous Names: Bram1 (1), bs69 (1), wu:fi38d06 (1), zgc:110370, zgc:152745

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Exhibits molecular function regulator. Involved in negative regulation of BMP signaling pathway and pathway-restricted SMAD protein phosphorylation. Is expressed in gut; head; immature eye; nervous system; and trunk. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 30. Orthologous to human ZMYND11 (zinc finger MYND-type containing 11).
Genome Resources: Alliance (1),  Gene:553781 (1),  Ensembl(GRCz11):ENSDARG00000057249 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb802 Small Deletion Exon 15 Frameshift CRISPR
ihb803 Insertion Exon 15 Frameshift CRISPR
la022956Tg Transgenic Insertion Unknown Unknown DNA
la022957Tg Transgenic Insertion Unknown Unknown DNA
sa6776 Point Mutation Unknown Premature Stop ENU
sa44159 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-zmynd11 1
    MO1-zmynd11 N/A 1
    DISEASE ASSOCIATED WITH zmynd11 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability 30 Alliance Mental retardation, autosomal dominant 30 616083
    DISEASE ASSOCIATED WITH zmynd11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of BMP signaling pathway (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zmynd11-202 (1)    Ensembl 3901
    ncRNA zmynd11-002 (1)    Ensembl 2437
    zmynd11-003 (1)    Ensembl 853
    zmynd11-004 (1)    Ensembl 1019
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zmynd11 No data available
    MARKER RELATIONSHIPS
    zmynd11 Contained in: [BAC] DKEY-181H23 (1) (order this)
    zmynd11 Encodes: [EST] fi38d06
    [cDNA] MGC:110370 (1), MGC:152745 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077583 (1) 2586 nt
    Genomic GenBank:BX571689 (1) 154608 nt
    Select Tool
    Polypeptide UniProtKB:A9UL18 (1) 640 aa
    Sequence Information (all 34)
    ORTHOLOGY for zmynd11 ( Chr: 24 )
    CITATIONS (24)