ZFIN ID: ZDB-GENE-050522-297
Gene Name: nucleoporin 88
Gene Symbol: nup88
Previous Names: ik:tdsubc_2f7, wu:fb16f10, wu:fb33e09, xx:tdsubc_2f7, zgc:112439
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 12 figures (10 images) from Rauch et al., 2003 [fb16f10]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
  brain, eye, immature eye, lens (all 10) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: nup88sa2206/sa2206(Tupfel long fin)

Allele Type Mutagen Suppliers
sa2206 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9811 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20552 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa20553 Point Mutation ENU
    PHENOTYPE
    Data: Fig. 1 from Busch-Nentwich et al., 2012
    Observed in: eye, head, melanocyte, swim bladder (all 5) expand
    DISEASE ASSOCIATED WITH nup88 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mRNA export from nucleus (more)
    Cellular Component nuclear pore (more)
    Molecular Function transporter activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR019321 (1)
  • Pfam:PF10168 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nup88-001 (1) 2410
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nup88 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nup88 Contained in: [BAC] CH211-284F22 (1) (order this)
    nup88 Encodes: [EST] fb16f10 (1) (order this), fb33e09 (1), fe14e10 (1), tdsubc_2f7 (1)
    [cDNA] MGC:112439 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020466 (1) 2422 bp
    Genomic GenBank:CR450697 (1) 143752 bp
    Select Tool
    Polypeptide UniProtKB:A2CEI4 (1) 720 aa
    Sequence Clusters UniGene:4121 (1)
    Sequence Information (all 16)
    OTHER nup88 GENE PAGES
  • Gene:321744 (1)
  • VEGA:OTTDARG00000018696 (1)
  • Ensembl(Zv9):ENSDARG00000003235 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish nup88 5  
    Human NUP88 17 (17p13.2)
  • OMIM:602552
  • Gene:4927
  • Mouse Nup88 11 ( 43.21 cM)
  • MGI:104900
  • Gene:19069
  • Orthology Details
    CITATIONS (18)