ZFIN ID: ZDB-GENE-050522-262
Gene Name: inter-alpha-trypsin inhibitor heavy chain 3a
Gene Symbol: itih3a    Nomenclature History

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Previous Name: zgc:110377

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in hyaluronan metabolic process. Is expressed in liver. Orthologous to human ITIH3 (inter-alpha-trypsin inhibitor heavy chain 3).
Genome Resources: Alliance (1),  Gene:553614 (1),  Ensembl(GRCz11):ENSDARG00000055036 (2)
GENE EXPRESSION
All Expression Data: Fig. s2 from Takada et al., 2017
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH itih3a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH itih3a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hyaluronan metabolic process (more)
Cellular Component cellular_component (more)
Molecular Function serine-type endopeptidase inhibitor activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR002035 von Willebrand factor, type A
Domain IPR010600 Inter-alpha-trypsin inhibitor heavy chain, C-terminal
Domain IPR013694 VIT domain
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA itih3a-201 (1)    Ensembl 2975
itih3a-202 (1)    Ensembl 810
ncRNA itih3a-003 (1)    Ensembl 651
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM itih3a No data available
MARKER RELATIONSHIPS
itih3a Contained in: [BAC] DKEY-33M11 (1) (order this)
itih3a Encodes: [cDNA] MGC:110377 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001020588 (1) 3026 nt
Genomic GenBank:CR558302 (1) 199875 nt
Select Tool
Polypeptide UniProtKB:F1QTF9 (1) 905 aa
Sequence Information (all 10)
ORTHOLOGY for itih3a ( Chr: 11 )
CITATIONS (16)