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Gene

cpb2

ID
ZDB-GENE-050522-259
Name
carboxypeptidase B2 (plasma)
Symbol
cpb2 Nomenclature History
Previous Names
  • zgc:112493 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in fibrinolysis and proteolysis. Predicted to be active in extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in chronic kidney disease. Orthologous to human CPB2 (carboxypeptidase B2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Takada et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cpb2 Human Ortholog
No data available
Associated With cpb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000834 Peptidase M14, carboxypeptidase A
Domain IPR003146 Carboxypeptidase, activation peptide
Homologous_superfamily IPR036990 Metallocarboxypeptidase-like, propeptide
Domain Details Per Protein
Protein Length Carboxypeptidase, activation peptide Metallocarboxypeptidase-like, propeptide Peptidase M14, carboxypeptidase A
UniProtKB:Q501X0 355
UniProtKB:A0A2R8QEK2 356
UniProtKB:E7F897 424
UniProtKB:F1Q6J5 355
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations