ZFIN ID: ZDB-GENE-050522-256
Gene Name: NIP7 nucleolar pre-rRNA processing protein
Gene Symbol: nip7    Nomenclature History

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Previous Name: zgc:110384 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to localize to the nucleolus and preribosome, large subunit precursor. Is expressed in several structures, including alar plate midbrain region; immature eye; liver; nervous system; and segmental plate. Orthologous to human NIP7 (nucleolar pre-rRNA processing protein NIP7).
Genome Resources: Alliance (1),  Gene:553616 (1),  Ensembl(GRCz11):ENSDARG00000059075 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32182 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nip7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nip7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ribosome assembly (more)
    Cellular Component nucleus (more)
    Molecular Function RNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002478 PUA domain
    Domain IPR005155 UPF0113, PUA domain
    Domain IPR040598 UPF0113, pre-PUA domain
    Family IPR016686 Ribosome biogenesis factor, NIP7
    Homologous_superfamily IPR015947 PUA-like superfamily
    Homologous_superfamily IPR036974 PUA domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nip7-002 (1) 614
    nip7-201 (1)    Ensembl 849
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nip7 No data available
    MARKER RELATIONSHIPS
    nip7 Contained in: [BAC] CH73-167I17 (1)
    nip7 Encodes: [EST] IMAGE:7158017 (1)
    [cDNA] MGC:110384 (1), MGC:192133 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020590 (1) 944 nt
    Genomic GenBank:CU927919 (1) 128751 nt
    Select Tool
    Polypeptide UniProtKB:B2GR20 (1) 180 aa
    Sequence Information (all 18)
    ORTHOLOGY for nip7 ( Chr: 18 )
    CITATIONS (22)