Gene

ptk7a

ID
ZDB-GENE-050522-216
Name
protein tyrosine kinase 7a
Symbol
ptk7a Nomenclature History
Previous Names
  • ptk7 (1)
  • zgc:112211
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and protein kinase activity. Involved in several processes, including cerebrospinal fluid circulation; negative regulation of canonical Wnt signaling pathway; and regulation of establishment of planar polarity. Predicted to localize to cell-cell junction. Is expressed in head; nervous system; neural tube; somite; and tail bud. Used to study idiopathic scoliosis and scoliosis. Orthologous to human PTK7 (protein tyrosine kinase 7 (inactive)).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptk7a Human Ortholog
No data available
Associated With ptk7a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008266 Tyrosine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Protein kinase domain Protein kinase-like domain superfamily Serine-threonine/tyrosine-protein kinase, catalytic domain Tyrosine-protein kinase, active site
UniProtKB:T1TF52 1061
UniProtKB:E7F2R9 1061
UniProtKB:F8W2W3 231
UniProtKB:Q502I0 231
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations