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ZIRC
ZFIN ID: ZDB-GENE-050522-158
Gene Name: ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Gene Symbol: uchl3    Nomenclature History

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Previous Names: im:6908825, zgc:109963 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have thiol-dependent ubiquitin-specific protease activity. Involved in Notch signaling pathway and cranial skeletal system development. Predicted to localize to the cytoplasm. Is expressed in notochord. Orthologous to human UCHL3 (ubiquitin C-terminal hydrolase L3).
Genome Resources: Alliance (1),  Gene:554104 (1),  Ensembl(GRCz11):ENSDARG00000030177 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [IMAGE:6908825]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11118 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41404 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-uchl3 N/A 2
    MO2-uchl3 N/A 1
    DISEASE ASSOCIATED WITH uchl3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH uchl3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cranial skeletal system development (more)
    Cellular Component cytoplasm (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA uchl3-201 (1)    Ensembl 1186
    ncRNA uchl3-002 (1)    Ensembl 677
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM uchl3 No data available
    MARKER RELATIONSHIPS
    uchl3 Contained in: [BAC] DKEY-57A22 (1) (order this)
    uchl3 Encodes: [EST] IMAGE:6908825 (1) (order this)
    [cDNA] MGC:109963 (1) (order this), MGC:191500 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001024405 (1) 964 bp
    Genomic GenBank:CR536604 (1) 217381 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q504C0 (1) 230 aa
    Sequence Clusters UniGene:47891 (1)
    Sequence Information (all 16)
    ORTHOLOGY for uchl3 ( Chr: 9 )
    CITATIONS (25)