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ZIRC
ZFIN ID: ZDB-GENE-050522-137
Gene Name: WW domain binding protein 2
Gene Symbol: wbp2    Nomenclature History

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Previous Name: zgc:109985

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have chromatin DNA binding activity and transcription coactivator activity. Predicted to be involved in cellular response to estrogen stimulus and positive regulation of gene expression, epigenetic. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 107. Orthologous to human WBP2 (WW domain binding protein 2).
Genome Resources: Alliance (1),  Gene:553565 (1),  Ensembl(GRCz11):ENSDARG00000056605 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH wbp2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 107 Alliance Deafness, autosomal recessive 107 617639
DISEASE ASSOCIATED WITH wbp2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to estrogen stimulus (more)
Cellular Component nuclear chromatin (more)
Molecular Function transcription coactivator activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004182 (1)
  • InterPro:IPR033598 (1)
  • Pfam:PF02893 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wbp2-201 (1)    Ensembl 3502
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wbp2 No data available
    MARKER RELATIONSHIPS
    wbp2 Contained in: [BAC] CH73-364M4 (1) (order this)
    wbp2 Encodes: [cDNA] MGC:109985 (1) (order this), MGC:192785 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020544 (1) 1339 bp
    Genomic GenBank:CU463233 (1) 106368 bp
    Select Tool
    Polypeptide UniProtKB:F1QJX3 (1) 264 aa
    Sequence Clusters UniGene:41776 (1)
    Sequence Information (all 15)
    ORTHOLOGY for wbp2 ( Chr: 12 )
    CITATIONS (12)