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ZIRC
ZFIN ID: ZDB-GENE-050522-123
Gene Name: TP53 regulating kinase
Gene Symbol: tp53rk    Nomenclature History

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Previous Names: fd05d02, wu:fd05d02, zgc:110000 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to localize to the EKC/KEOPS complex; cytosol; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase).
Genome Resources: Alliance (1),  Gene:553571 (1),  Ensembl(GRCz11):ENSDARG00000112667 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6907866]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017765Tg Transgenic Insertion Unknown Unknown DNA
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tp53rk HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Galloway-Mowat syndrome 4 Alliance Galloway-Mowat syndrome 4 617730
DISEASE ASSOCIATED WITH tp53rk VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process protein phosphorylation (more)
Cellular Component EKC/KEOPS complex (more)
Molecular Function ATP binding (more)
GO Terms (all 7)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA tp53rk-001 (1) 1651
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tp53rk No data available
MARKER RELATIONSHIPS
tp53rk Contained in: [BAC] CH73-267C23 (1) (order this)
tp53rk Encodes: [EST] fd05d02, IMAGE:6907866 (1) (order this)
[cDNA] MGC:110000 (1) (order this), MGC:192236 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001020550 (1) 1257 bp
Genomic GenBank:CU928126 (1) 115406 bp
Select Tool
Polypeptide UniProtKB:F1QB90 (1) 231 aa
Sequence Clusters UniGene:31620 (1)
Sequence Information (all 19)
ORTHOLOGY for tp53rk ( Chr: 11 )
CITATIONS (21)