ZFIN ID: ZDB-GENE-050522-102
Gene Name: neuralized E3 ubiquitin protein ligase 1B
Gene Symbol: neurl1b    Nomenclature History

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Previous Names: si:dkey-203a12.1, zgc:110426

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent endocytosis. Predicted to localize to the early endosome. Is expressed in adaxial cell; cardiovascular system; myotome; and somite. Orthologous to human NEURL1B (neuralized E3 ubiquitin protein ligase 1B).
Genome Resources: Alliance (1),  Gene:553620 (1),  Ensembl(GRCz11):ENSDARG00000099694 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31979 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH neurl1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH neurl1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ubiquitin-dependent endocytosis (more)
    Cellular Component early endosome (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR006573 Neuralized homology repeat (NHR) domain
    Family IPR037962 Neuralized
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript neurl1b-203 (1)    Ensembl 1710
    mRNA neurl1b-201 (1)    Ensembl 4003
    neurl1b-202 (1)    Ensembl 647
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM neurl1b No data available
    MARKER RELATIONSHIPS
    neurl1b Contained in: [BAC] CH211-168N2 (1), CH211-198F4 (1), DKEY-203A12 (1) (order this)
    neurl1b Encodes: [cDNA] MGC:110426 (1), MGC:192044 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020594 (1) 1727 nt
    Genomic GenBank:CR381700 (1) 203630 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QF54 (1) 579 aa
    Sequence Information (all 21)
    ORTHOLOGY for neurl1b ( Chr: 14 )
    CITATIONS (15)