ZFIN ID: ZDB-GENE-050517-9
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 6a
Gene Symbol: abcb6a
Previous Name: abcb6
Location: Chr: 1   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 3 from Wang et al., 2012
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la013705Tg, sa19409, sa19410
Knockdown reagents: MO1-abcb6a (1), MO2-abcb6a (1), MO3-abcb6a (1), MO4-abcb6a (1), MO5-abcb6a (1) (all 6) expand
PHENOTYPE
Data: 3 figures from 2 publications
Observed in: embryo development, head melanocyte, iris, pupil

Phenotype of Human Orthologue OMIM Phenotype ID
Dyschromatosis universalis hereditaria 3 615402
Microphthalmia, isolated, with coloboma 7 614497
[Blood group, Langereis system] 111600
GENE ONTOLOGY
Ontology GO Term
Biological Process iris morphogenesis (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001140 (1)
  • InterPro:IPR003439 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR011527 (1)
  • InterPro:IPR017871 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS00211 (1)
  • PROSITE:PS50893 (1)
  • PROSITE:PS50929 (1)
  • Pfam:PF00005 (1)
  • Pfam:PF00664 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abcb6a-001 (1) 2950
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcb6a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    abcb6a Contained in: [BAC] CH211-103I6 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145693 (1) 2939 bp
    Genomic GenBank:BX004814 (1) 171710 bp
    Select Tool
    Polypeptide UniProtKB:F1QCK2 (1) 851 aa
    Sequence Clusters UniGene:110905 (1)
    Sequence Information (all 11)
    OTHER abcb6a GENE PAGES
  • Gene:564067 (1)
  • VEGA:OTTDARG00000029811 (1)
  • Ensembl(Zv9):ENSDARG00000063297 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL FC
    Zebrafish abcb6a 1  
    Human ABCB6 2 (2q36)
  • OMIM:605452
  • Gene:10058
  • Orthology Details
    CITATIONS (19)