ZFIN ID: ZDB-GENE-050517-9
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 6a
Gene Symbol: abcb6a
Previous Name: abcb6
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 3 from Wang et al., 2012
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la013705Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19409 Point Mutation ENU
    sa19410 Point Mutation ENU
    Targeting reagents: MO1-abcb6a (1), MO2-abcb6a (1), MO3-abcb6a (1), MO4-abcb6a (1), MO5-abcb6a (1) (all 6) expand
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in: embryo development, head melanocyte, iris, pupil
    DISEASE ASSOCIATED WITH abcb6a HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dyschromatosis universalis hereditaria Dyschromatosis universalis hereditaria 3 615402
    Microphthalmia, isolated, with coloboma 7 614497
    Pseudohyperkalemia, familial, 2, due to red cell leak 609153
    Pseudohyperkalemia, familial, 2, due to red cell leak 609153
    [Blood group, Langereis system] 111600
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process iris morphogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR011527 (1)
  • InterPro:IPR017871 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR032410 (1)
  • PROSITE:PS00211 (1)
  • PROSITE:PS50893 (1)
  • PROSITE:PS50929 (1)
  • Pfam:PF00005 (1)
  • Pfam:PF00664 (1)
  • Pfam:PF16185 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abcb6a-001 (1) 2950
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcb6a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    abcb6aContained in: [BAC] CH211-103I6 (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145693 (1) 2939bp
    Genomic GenBank:BX004814 (1) 171710bp
    Select Tool
    Polypeptide UniProtKB:F1QCK2 (1) 851aa
    Sequence Clusters UniGene:110905 (1)
    Sequence Information (all 11)
    OTHER abcb6a GENE PAGES 
  • Gene:564067 (1)
  • VEGA:OTTDARG00000029811 (1)
  • Ensembl(GRCz10):ENSDARG00000063297 (1)
  • ORTHOLOGY for abcb6a (Chr: 1) 
    Species Symbol Chromosome Accession # Evidence
    Human ABCB6 2
  • Gene:10058
  • OMIM:605452
  • HGNC:47
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Functional complementation (1)
    Mouse Abcb6 1
  • MGI:1921354
  • Gene:74104
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (20)