| ZFIN ID: ZDB-GENE-050517-40 |
| Gene Name: | ATP-binding cassette, sub-family G (WHITE), member 5 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene Symbol: | abcg5 Nomenclature History |
{{control.fieldName}} Edit
Attributions
|
||||||||||||
| Previous Name: | sterolin 1 | |||||||||||||
Add new Alias
Attributions for Alias: {{control.newAlias}}
Delete Alias:(Including Attributions) |
||||||||||||||
| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 13 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis and transmembrane transport. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:557317 (1), Ensembl(GRCz11):ENSDARG00000063078 (1) | |||||||||||||
| All Expression Data: | Fig. 2 from Pinto et al., 2016 |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| sa2683 | Point Mutation | Unknown | Premature Stop | ENU | |
| sa17622 | Point Mutation | Unknown | Premature Stop | ENU |
|
| sa22240 | Point Mutation | Unknown | Splice Site | ENU |
|
| sa42150 | Point Mutation | Unknown | Premature Stop | ENU |
|
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sitosterolemia 2 | 618666 |
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | cholesterol homeostasis (more) |
| Cellular Component | integral component of membrane (more) |
| Molecular Function | ATPase activity (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
abcg5-201
(1)
|
2471 |
Select Tool
|
| Browsers: UCSC, NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM abcg5
No data available
MARKER RELATIONSHIPS
| abcg5 Contained in: | [BAC] CH211-227C6 (1) |
| abcg5 Encodes: | [cDNA] MGC:193792 (1), MGC:193804 (1) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_001128690 (1) | 2054 nt |
Select Tool
|
| Genomic | GenBank:AL928999 (1) | 169570 nt | |
| Polypeptide | UniProtKB:B3DG12 (1) | 652 aa |
Select Tool
|
ORTHOLOGY for abcg5 (
Chr:
13
)
CITATIONS (24)