Gene
abcg5
- ID
- ZDB-GENE-050517-40
- Name
- ATP-binding cassette, sub-family G (WHITE), member 5
- Symbol
- abcg5 Nomenclature History
- Previous Names
-
- sterolin 1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Pinto et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Sitosterolemia 2 | 618666 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017871 | ABC transporter, conserved site |
Domain | IPR003439 | ABC transporter-like |
Domain | IPR003593 | AAA+ ATPase domain |
Domain | IPR013525 | ABC-2 type transporter |
Domain | IPR043926 | ABC transporter family G domain |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | AAA+ ATPase domain | ABC-2 type transporter | ABC transporter, conserved site | ABC transporter family G domain | ABC transporter-like | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|---|
UniProtKB:B3DG12
|
652 |
Interactions and Pathways
No data available
Plasmids
No data available