Gene

abcg5

ID
ZDB-GENE-050517-40
Name
ATP-binding cassette, sub-family G (WHITE), member 5
Symbol
abcg5 Nomenclature History
Previous Names
  • sterolin 1
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Pinto et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abcg5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sitosterolemia 2 618666
Associated With abcg5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Domain IPR013525 ABC-2 type transporter
Domain IPR043926 ABC transporter family G domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC-2 type transporter ABC transporter, conserved site ABC transporter family G domain ABC transporter-like P-loop containing nucleoside triphosphate hydrolase
UniProtKB:B3DG12 652
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations