Gene

abcg5

ID

ZDB-GENE-050517-40

Name

ATP-binding cassette, sub-family G (WHITE), member 5

Symbol

abcg5 Nomenclature History

Previous Names

sterolin 1

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Pinto et al., 2016

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcg5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Sitosterolemia 2	618666

Associated With abcg5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter, conserved site
Domain	IPR003439	ABC transporter-like
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013525	ABC-2 type transporter
Domain	IPR043926	ABC transporter family G domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase