ZFIN ID: ZDB-GENE-050517-40
Gene Name: ATP-binding cassette, sub-family G (WHITE), member 5
Gene Symbol: abcg5    Nomenclature History

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Previous Name: sterolin 1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled transmembrane transporter activity. Predicted to be involved in cholesterol homeostasis and transmembrane transport. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5).
Genome Resources: Alliance (1),  Gene:557317 (1),  Ensembl(GRCz11):ENSDARG00000063078 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Pinto et al., 2016
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2683 Point Mutation Unknown Premature Stop ENU
sa17622 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22240 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42150 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abcg5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Sitosterolemia 2 618666
    DISEASE ASSOCIATED WITH abcg5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cholesterol homeostasis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abcg5-201 (1)    Ensembl 2471
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcg5 No data available
    MARKER RELATIONSHIPS
    abcg5 Contained in: [BAC] CH211-227C6 (1)
    abcg5 Encodes: [cDNA] MGC:193792 (1), MGC:193804 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128690 (1) 2054 nt
    Genomic GenBank:AL928999 (1) 169570 nt
    Select Tool
    Polypeptide UniProtKB:B3DG12 (1) 652 aa
    Sequence Information (all 11)
    ORTHOLOGY for abcg5 ( Chr: 13 )
    CITATIONS (24)