Gene

abcg2a

ID

ZDB-GENE-050517-35

Name

ATP-binding cassette, sub-family G (WHITE), member 2a

Symbol

abcg2a Nomenclature History

Previous Names

fd59c01
wu:fd59c01

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Localizes to ATP-binding activity cassette (ABC) transporter complex. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Is expressed in hematopoietic stem cell; intestine; and kidney. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcg2a Human Ortholog

No data available

Associated With abcg2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013525	ABC-2 type transporter, transmembrane domain
Domain	IPR043926	ABC transporter family G domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase