Gene

abcg2a

ID
ZDB-GENE-050517-35
Name
ATP-binding cassette, sub-family G (WHITE), member 2a
Symbol
abcg2a Nomenclature History
Previous Names
  • fd59c01
  • wu:fd59c01
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; ATPase activity; and ATPase-coupled xenobiotic transmembrane transporter activity. Predicted to be involved in transmembrane transport. Localizes to ATP-binding activity cassette (ABC) transporter complex. Is expressed in hematopoietic stem cell; intestine; and kidney. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from Kobayashi et al., 2008
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abcg2a Human Ortholog
No data available
Associated With abcg2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Domain IPR013525 ABC-2 type transporter
Family IPR030256 ATP-binding cassette subfamily G member 2
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC-2 type transporter ABC transporter-like ATP-binding cassette subfamily G member 2 P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A0J9YJL0 412
UniProtKB:A0A0R4IUY7 643
UniProtKB:Q2Q447 643
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations