Gene

abca3b

ID
ZDB-GENE-050517-2
Name
ATP-binding cassette, sub-family A (ABC1), member 3b
Symbol
abca3b Nomenclature History
Previous Names
  • abca3
  • si:ch211-155i15.6
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in swim bladder. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chen et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abca3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pulmonary alveolar proteinosis Alliance Surfactant metabolism dysfunction, pulmonary, 3 610921
Associated With abca3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Family IPR026082 ABC transporter A
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC transporter A ABC transporter, conserved site ABC transporter-like P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A0R4ISK5 1703
UniProtKB:A0A2R8Q955 1754
UniProtKB:A0A0R4IUM5 1126
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations