ZFIN ID: ZDB-GENE-050517-2
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 3b
Gene Symbol: abca3b    Nomenclature History

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Previous Names: abca3, si:ch211-155i15.6

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in swim bladder. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000100524 (1)
GENE EXPRESSION
All Expression Data: Fig. 8 from Chen et al., 2018
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33105 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40008 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abca3b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    pulmonary alveolar proteinosis Alliance Surfactant metabolism dysfunction, pulmonary, 3 610921
    DISEASE ASSOCIATED WITH abca3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abca3b-202 (1)    Ensembl 4994
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abca3b No data available
    MARKER RELATIONSHIPS
    abca3b Contained in: [BAC] CH211-155I15 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    Genomic GenBank:AL929078 (1) 171571 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q955 (1) 1754 aa
    Sequence Information (all 4)
    ORTHOLOGY for abca3b ( Chr: 3 )
    CITATIONS (19)