Gene

abcc6b.1

ID
ZDB-GENE-050517-19
Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
Symbol
abcc6b.1 Nomenclature History
Previous Names
  • abcc6b
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to membrane. Is expressed in EVL; dermal bone; inner ear; opercular flap; and pronephric proximal straight tubule. Human ortholog(s) of this gene implicated in arterial calcification of infancy; coronary artery disease; and pseudoxanthoma elasticum. Orthologous to human ABCC6 (ATP binding cassette subfamily C member 6).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abcc6b.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
arterial calcification of infancy Alliance Arterial calcification, generalized, of infancy, 2 614473
pseudoxanthoma elasticum Alliance Pseudoxanthoma elasticum 264800
pseudoxanthoma elasticum Alliance Pseudoxanthoma elasticum, forme fruste 177850
Associated With abcc6b.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Domain IPR011527 ABC transporter type 1, transmembrane domain
Family IPR030239 Multidrug resistance-associated protein 6
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036640 ABC transporter type 1, transmembrane domain superfamily
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC transporter, conserved site ABC transporter-like ABC transporter type 1, transmembrane domain ABC transporter type 1, transmembrane domain superfamily Multidrug resistance-associated protein 6 P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A2R8Q5X0 196
UniProtKB:A0A140LFR5 161
UniProtKB:A0A140LGD8 904
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations