Gene
abcc1
- ID
- ZDB-GENE-050517-15
- Name
- ATP binding cassette subfamily C member 1 (ABCC1 blood group)
- Symbol
- abcc1 Nomenclature History
- Previous Names
-
- mrp1 (1)
- si:dkeyp-72e1.5
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATPase-coupled transmembrane transporter activity. Involved in detoxification of cadmium ion. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human ABCC1 (ATP binding cassette subfamily C member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 77 | Alliance | ?Deafness, autosomal dominant 77 | 618915 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Family | IPR005292 | Multi drug resistance-associated protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | Multi drug resistance-associated protein | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IC81
|
1518 |
Interactions and Pathways
No data available
Plasmids
No data available