ZFIN ID: ZDB-GENE-050506-78
Gene Name: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Gene Symbol: fdps    Nomenclature History

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Previous Names: fb23g06, im:6904202, wu:fb23g06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process. Predicted to localize to cytoplasm. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human FDPS (farnesyl diphosphate synthase).
Genome Resources: Alliance (1),  Gene:552997 (1),  Ensembl(GRCz11):ENSDARG00000040890 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 5 figures (6 images) from Thisse et al., 2004 [IMAGE:6904202]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019564Tg Transgenic Insertion Unknown Unknown DNA
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fdps HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Porokeratosis 9, multiple types 616631
DISEASE ASSOCIATED WITH fdps VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process isoprenoid biosynthetic process (more)
Cellular Component cytoplasm (more)
Molecular Function transferase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA fdps-201 (1)    Ensembl 958
fdps-202 (1)    Ensembl 2212
fdps-203 (1)    Ensembl 937
ncRNA fdps-004 (1)    Ensembl 996
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fdps No data available
MARKER RELATIONSHIPS
fdps Contained in: [BAC] DKEY-85K15 (1) (order this)
fdps Encodes: [EST] fb23g06, IMAGE:6904202 (1)
[cDNA] MGC:114048 (1), MGC:191573 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001025471 (1) 1836 nt
Genomic GenBank:BX005429 (1) 173571 nt
Select Tool
Polypeptide UniProtKB:A0A2R8Q157 (1) 362 aa
Sequence Information (all 21)
ORTHOLOGY for fdps ( Chr: 16 )
CITATIONS (32)