Gene

fdps

ID
ZDB-GENE-050506-78
Name
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Symbol
fdps Nomenclature History
Previous Names
  • fb23g06
  • im:6904202
  • wu:fb23g06
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process. Predicted to localize to cytoplasm. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human FDPS (farnesyl diphosphate synthase).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fdps Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Porokeratosis 9, multiple types 616631
Associated With fdps Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR033749 Polyprenyl synthetase, conserved site
Family IPR000092 Polyprenyl synthetase
Family IPR039702 Farnesyl pyrophosphate synthase-like
Homologous_superfamily IPR008949 Isoprenoid synthase domain superfamily
Domain Details Per Protein
Protein Length Farnesyl pyrophosphate synthase-like Isoprenoid synthase domain superfamily Polyprenyl synthetase Polyprenyl synthetase, conserved site
UniProtKB:E9QE30 316
UniProtKB:Q5XJ03 359
UniProtKB:F1QN60 312
UniProtKB:A0A2R8Q157 362
UniProtKB:F1QEG3 356
UniProtKB:Q4V916 356
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations