Community Action Needed: Please respond to the NIH RFI
Gene

vps25

ID
ZDB-GENE-050506-30
Name
vacuolar protein sorting 25 homolog
Symbol
vps25 Nomenclature History
Previous Names
  • im:6898134
  • zgc:162560
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable protein homodimerization activity and structural molecule activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within multivesicular body sorting pathway and protein transport. Predicted to be located in cytoplasm. Predicted to be part of ESCRT II complex. Orthologous to human VPS25 (vacuolar protein sorting 25 homolog).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps25 Human Ortholog
No data available
Associated With vps25 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008570 ESCRT-II complex, Vps25 subunit
Homologous_superfamily IPR014041 ESCRT-II complex, Vps25 subunit, N-terminal winged helix
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length ESCRT-II complex, Vps25 subunit ESCRT-II complex, Vps25 subunit, N-terminal winged helix Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A4QN77 174
UniProtKB:F1QSR5 174
UniProtKB:Q6NWF4 174
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations