ZFIN ID: ZDB-GENE-050506-143
Gene Name: eps8 like 1b
Gene Symbol: eps8l1b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: im:7147678 (1), si:ch73-70c5.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to contribute to Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in Rho protein signal transduction; positive regulation of ruffle assembly; and regulation of Rho protein signal transduction. Predicted to localize to ruffle membrane. Orthologous to human EPS8L1 (EPS8 like 1).
Genome Resources: Alliance (1),  Gene:553062 (1),  Ensembl(GRCz11):ENSDARG00000003313 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7147678]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24555 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37957 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eps8l1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eps8l1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of ruffle assembly (more)
    Cellular Component plasma membrane (more)
    Molecular Function actin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA eps8l1b-202 (1)    Ensembl 734
    eps8l1b-203 (1)    Ensembl 2635
    ncRNA si:ch73-70c5.1-003 (1) 554
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eps8l1b No data available
    MARKER RELATIONSHIPS
    eps8l1b Contained in: [BAC] CH73-70C5 (1)
    [Fosmid] CH1073-164K15 (1)
    eps8l1b Encodes: [EST] IMAGE:7147678 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005170798 (1) 2204 nt
    Genomic GenBank:FP102170 (1) 109374 nt
    Select Tool
    Polypeptide UniProtKB:E7F1L9 (1) 505 aa
    Sequence Information (all 11)
    ORTHOLOGY for eps8l1b ( Chr: 24 )
    CITATIONS (13)