ZFIN ID: ZDB-GENE-050506-134
Gene Name: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Gene Symbol: lrp8    Nomenclature History

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Previous Names: apoer2 (1), im:7145907 (1), si:dkeyp-63d11.7 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Predicted to localize to integral component of membrane. Is expressed in several structures, including axial hypoblast; brain; immature eye; neural tube; and neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; dementia; myocardial infarction; and schizophrenia. Orthologous to human LRP8 (LDL receptor related protein 8).
Genome Resources: Alliance (1),  Gene:557734 (1),  Ensembl(GRCz11):ENSDARG00000070074 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH lrp8 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Myocardial infarction, susceptibility to} 608446
DISEASE ASSOCIATED WITH lrp8 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component integral component of membrane (more)
Molecular Function calcium ion binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lrp8-201 (1)    Ensembl 8651
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lrp8 No data available
MARKER RELATIONSHIPS
lrp8 Contained in: [BAC] DKEY-50M7 (1) (order this), DKEY-61C16 (1) (order this), DKEYP-63D11 (1)
lrp8 Encodes: [EST] IMAGE:7145907 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001256393 (1)
Genomic RefSeq:NW_018395381 (1) Blast at MegaBLAST
Polypeptide UniProtKB:H3K2Y7 (1) 988 aa
Sequence Information (all 25)
ORTHOLOGY for lrp8 ( Chr: 6 )
CITATIONS (24)