Gene

hmgb3a

ID
ZDB-GENE-050428-1
Name
high mobility group box 3a
Symbol
hmgb3a Nomenclature History
Previous Names
  • wu:fb17a03
  • wu:fk52f12
  • zgc:162415
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA binding activity, bending and transcription factor binding activity. Predicted to be involved in several processes, including chromatin remodeling; positive regulation of innate immune response; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nuclear chromatin. Human ortholog(s) of this gene implicated in syndromic microphthalmia. Is expressed in several structures, including axis; intermediate cell mass of mesoderm; mesoderm; nervous system; and pectoral fin bud. Orthologous to human HMGB3 (high mobility group box 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hmgb3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic microphthalmia 13 Alliance ?Microphthalmia, syndromic 13 300915
Associated With hmgb3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length High mobility group box domain High mobility group box domain superfamily
UniProtKB:F1QGP8 213
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations