ZFIN ID: ZDB-GENE-050420-7
Gene Name: mitogen-activated protein kinase 6
Gene Symbol: mapk6    Nomenclature History

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Previous Names: ERK3 (1), si:ch211-235f12.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have MAP kinase activity. Predicted to be involved in intracellular signal transduction and regulation of gene expression. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; otic vesicle; and pectoral fin. Orthologous to human MAPK6 (mitogen-activated protein kinase 6).
Genome Resources: Alliance (1),  Gene:565830 (1),  Ensembl(GRCz11):ENSDARG00000032103 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36705 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36706 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mapk6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mapk6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mapk6-201 (1)    Ensembl 2963
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mapk6 No data available
    MARKER RELATIONSHIPS
    mapk6 Contained in: [BAC] CH211-235F12 (1)
    mapk6 Encodes: [cDNA] MGC:194232 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045552 (1) 2190 nt
    Genomic GenBank:AL935189 (1) 170193 nt
    Select Tool
    Polypeptide UniProtKB:Q0H1F2 (1) 729 aa
    Sequence Information (all 17)
    ORTHOLOGY for mapk6 ( Chr: 18 )
    CITATIONS (26)