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General Information
ZIRC
ZFIN ID: ZDB-GENE-050420-347
Gene Name: FYVE, RhoGEF and PH domain containing 4a
Gene Symbol: fgd4a
Sequence Ontology ID : SO:0000704

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Previous Names: fgd4, si:ch211-194i18.1, si:dkey-57m7.1

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Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
Note: This gene has an almost identical sequence to si:dkey-57m7.1. The EST CK683166 matches both.
AUTOMATED DESCRIPTION
Predicted to have Rho guanyl-nucleotide exchange factor activity and metal ion binding activity. Predicted to be involved in regulation of Rho protein signal transduction. Human ortholog(s) of this  ...
GENE EXPRESSION
Directly Submitted Expression Data: 4 figures (4 images) from Thisse et al., 2004 [IMAGE:7145382]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fgd4a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 4H Charcot-Marie-Tooth disease, type 4H 609311
DISEASE ASSOCIATED WITH fgd4a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of Rho protein signal transduction (more)
Molecular Function guanyl-nucleotide exchange factor activity (more)
GO Terms (all 4)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA fgd4a-201 (1) 479
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM fgd4a No data available
MARKER RELATIONSHIPS
fgd4aContained in: [BAC] CH211-136I24 (1) (order this), CH211-194I18 (1) (order this)
fgd4aEncodes: [EST] IMAGE:7145382 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001177933 (1) 3451bp
Genomic GenBank:CR293524 (1) 190196bp
Select Tool
Polypeptide UniProtKB:A0A0R4ILP5 (1) 728aa
Sequence Clusters UniGene:158966 (1)
Sequence Information (all 21)
ORTHOLOGY for fgd4a (Chr: 18)
CITATIONS (16)