ZFIN ID: ZDB-GENE-050420-181
Gene Name: acyl-CoA synthetase long chain family member 3a
Gene Symbol: acsl3a    Nomenclature History

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Previous Name: si:dkeyp-109h9.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Predicted to localize to endoplasmic reticulum; lipid droplet; and plasma membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma; breast cancer; and prostate cancer. Orthologous to human ACSL3 (acyl-CoA synthetase long chain family member 3).
Genome Resources: Alliance (1),  Gene:567157 (1),  Ensembl(GRCz11):ENSDARG00000032079 (2)
GENE EXPRESSION
All Expression Data: Fig. 6 from Lopes-Marques et al., 2013
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH acsl3a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH acsl3a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process long-chain fatty acid metabolic process (more)
Cellular Component integral component of membrane (more)
Molecular Function catalytic activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA acsl3a-201 (1)    Ensembl 2244
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM acsl3a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(fabp2:EGFP-acsl3a) fabp2 acsl3aEGFP Danio rerio 1 2
MARKER RELATIONSHIPS
acsl3a Contained in: [BAC] DKEYP-109H9 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045128 (1) 2142 nt
Genomic GenBank:BX890602 (1) 191296 nt
Select Tool
Polypeptide UniProtKB:Q1LVA8 (1) 713 aa
Sequence Information (all 8)
ORTHOLOGY for acsl3a ( Chr: 15 )
CITATIONS (24)