ZFIN ID: ZDB-GENE-050419-93
Gene Name: otogelin-like
Gene Symbol: otogl    Nomenclature History

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Previous Name: si:dkeyp-27b10.2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have alpha-L-arabinofuranosidase activity. Involved in otolith morphogenesis; semicircular canal morphogenesis; and sensory perception of sound. Predicted to localize to integral component of membrane. Is expressed in inner ear; macula utricle; and otolith. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 84B. Orthologous to human OTOGL (otogelin like).
Genome Resources: Alliance (1),  Gene:555569 (1),  Ensembl(GRCz11):ENSDARG00000088750 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013338Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la020531Tg Transgenic Insertion Unknown Unknown DNA
    sa2976 Point Mutation Unknown Premature Stop ENU
    sa9582 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16038 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23212 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25051 Point Mutation Unknown Splice Site ENU
    sa43033 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45627 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-otogl N/A 1
    MO2-otogl N/A 1
    DISEASE ASSOCIATED WITH otogl HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal recessive nonsyndromic deafness 84B Alliance Deafness, autosomal recessive 84B 614944
    DISEASE ASSOCIATED WITH otogl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process otolith morphogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function alpha-L-arabinofuranosidase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA otogl-201 (1)    Ensembl 8177
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM otogl No data available
    MARKER RELATIONSHIPS
    otogl Contained in: [BAC] CH73-25I22 (1), DKEYP-27B10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_021467952 (1)
    Genomic GenBank:BX546485 (1) 153332 nt
    Select Tool
    Polypeptide UniProtKB:F1Q539 (1) 2489 aa
    Sequence Information (all 16)
    ORTHOLOGY for otogl ( Chr: 18 )
    CITATIONS (22)