Gene

skor1b

ID

ZDB-GENE-050419-82

Name

SKI family transcriptional corepressor 1b

Symbol

skor1b Nomenclature History

Previous Names

si:dkey-246a16.3 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have SMAD binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of BMP signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and transcription factor complex. Is expressed in Purkinje cell. Orthologous to human SKOR1 (SKI family transcriptional corepressor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Takeuchi et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With skor1b Human Ortholog

No data available

Associated With skor1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003380	SKI/SNO/DAC domain
Domain	IPR014890	c-SKI SMAD4-binding domain
Family	IPR023216	Transcription regulator SKI/SnoN
Homologous_superfamily	IPR009061	Putative DNA-binding domain superfamily
Homologous_superfamily	IPR010919	SAND-like domain superfamily
Homologous_superfamily	IPR037000	Ski-like, DNA-binding domain superfamily