ZFIN ID: ZDB-GENE-050419-75
Gene Name: pleckstrin homology domain containing, family A member 7a
Gene Symbol: plekha7a    Nomenclature History

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Previous Names: plekha7, hadp1 (1), si:dkey-29p10.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have delta-catenin binding activity. Involved in cardiac muscle cell differentiation and regulation of heart contraction. Predicted to localize to centrosome and zonula adherens. Is expressed in cardiovascular system and tail bud. Orthologous to human PLEKHA7 (pleckstrin homology domain containing A7).
Genome Resources: Alliance (1),  Gene:571486 (1),  Ensembl(GRCz11):ENSDARG00000060813 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020367Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6523 Point Mutation Unknown Splice Site ENU
    sa23317 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29048 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43121 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-plekha7a N/A 2
    MO2-plekha7a N/A 1
    DISEASE ASSOCIATED WITH plekha7a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH plekha7a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle cell differentiation (more)
    Cellular Component centrosome (more)
    Molecular Function delta-catenin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA plekha7a-202 (1)    Ensembl 3838
    plekha7a-203 (1)    Ensembl 1319
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM plekha7a No data available
    MARKER RELATIONSHIPS
    plekha7a Contained in: [BAC] DKEY-29P10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001136243 (1) 3654 nt
    Genomic GenBank:BX640463 (1) 233058 nt Blast at MegaBLAST
    Polypeptide RefSeq:NP_001129715 (1) 1197 aa
    Sequence Information (all 8)
    ORTHOLOGY for plekha7a ( Chr: 18 )
    CITATIONS (20)