ZFIN Gene: afdna

ZFIN ID: ZDB-GENE-050419-52

ZFIN ID: ZDB-GENE-050419-52

Gene Name:

afadin, adherens junction formation factor a

Gene Symbol:

afdna

Sequence Ontology ID :

SO:0000704

Previous Names:

mllt4, mllt4a (1), si:ch211-278j12.1

Location:

Chr: 20 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have cell adhesion molecule binding activity. Predicted to be involved in regulation of protein localization. Predicted to localize to the cell-cell adherens junction. Orthologous to ...

GENE EXPRESSION No data available

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa11340	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this)
sa11351	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa11362	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37138	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37139	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37140	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE No data available

DISEASE ASSOCIATED WITH afdna HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH afdna VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	signal transduction (more)
Cellular Component	cell-cell adherens junction (more)
Molecular Function	cell adhesion molecule binding (more)

GO Terms (all 5)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000159 (1) InterPro:IPR000253 (1) InterPro:IPR001478 (1) InterPro:IPR002710 (1) InterPro:IPR008984 (1) InterPro:IPR029071 (1) InterPro:IPR036034 (1) InterPro:IPR037977 (1)	PROSITE:PS50106 (1) PROSITE:PS50200 (1) PROSITE:PS51126 (1)	Pfam:PF00498 (1) Pfam:PF00595 (1) Pfam:PF00788 (1) Pfam:PF01843 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	afdna-202 (1)	8628	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM afdna No data available

MARKER RELATIONSHIPS

afdnaContained in:

[BAC] CH211-278J12 (1) (order this), DKEY-14A7 (1) (order this), DKEY-286H23 (1) (order this), DKEYP-95D10 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_021468676 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:AL928920 (1)	195351bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:E7F4R0 (1)	1976aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 49)

OTHER afdna GENE PAGES

Alliance (1)

Gene:558359 (1)

VEGA:OTTDARG00000012561 (1)

Ensembl(GRCz11):ENSDARG00000029472 (2)

ORTHOLOGY for afdna (Chr: 20)

CITATIONS (17)

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