Gene
afdna
- ID
- ZDB-GENE-050419-52
- Name
- afadin, adherens junction formation factor a
- Symbol
- afdna Nomenclature History
- Previous Names
-
- mllt4
- mllt4a (1)
- si:ch211-278j12.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Is predicted to enable cell adhesion molecule binding activity. Involved in regulation of protein localization. Acts upstream of or within cell adhesion and signal transduction. Orthologous to human AFDN (afadin, adherens junction formation factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating (RA) domain |
| Domain | IPR000253 | Forkhead-associated (FHA) domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR002710 | Dilute domain |
| Domain | IPR037977 | Afadin, cargo binding domain |
| Homologous_superfamily | IPR008984 | SMAD/FHA domain superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | Afadin, cargo binding domain | Dilute domain | Forkhead-associated (FHA) domain | PDZ domain | PDZ superfamily | Ras-associating (RA) domain | SMAD/FHA domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:U3JA65
|
1927 | ||||||||
|
UniProtKB:E7F4R0
|
1976 |
Interactions and Pathways
No data available
Plasmids
No data available