Gene

alpk3a

ID
ZDB-GENE-050419-48
Name
alpha-kinase 3a
Symbol
alpk3a Nomenclature History
Previous Names
  • si:dkey-77f17.3
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and muscle alpha-actinin binding activity. Predicted to be involved in cardiac muscle tissue morphogenesis; striated muscle cell development; and striated muscle contraction. Predicted to localize to M band; Z disc; and striated muscle thin filament. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human ALPK3 (alpha kinase 3).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alpk3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cardiomyopathy, familial hypertrophic 27 618052
Associated With alpk3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR004166 MHCK/EF2 kinase
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 MHCK/EF2 kinase Protein kinase-like domain superfamily
UniProtKB:E7FFN2 196
UniProtKB:F1QB91 428
UniProtKB:M9MMA7 636
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations