Community Action Needed: Please respond to the NIH RFI
Gene

uacaa

ID
ZDB-GENE-050419-37
Name
uveal autoantigen with coiled-coil domains and ankyrin repeats a
Symbol
uacaa Nomenclature History
Previous Names
  • uaca
  • si:dkey-9i9.4
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to be involved in negative regulation of NIK/NF-kappaB signaling and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to act upstream of or within apoptotic signaling pathway and regulation of NIK/NF-kappaB signaling. Predicted to be active in cytosol and nucleus. Orthologous to human UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With uacaa Human Ortholog
No data available
Associated With uacaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020683 Ankyrin repeat-containing domain
Family IPR030227 Protein Nucling
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily Protein Nucling
UniProtKB:A8E7S7 761
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations