Gene

large2

ID
ZDB-GENE-050419-253
Name
LARGE xylosyl- and glucuronyltransferase 2
Symbol
large2 Nomenclature History
Previous Names
  • large2 (1)
  • gyltl1b (1)
  • si:ch211-206g24.1
  • si:ch211-282n12.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Is predicted to enable glucuronosyltransferase activity and xylosyltransferase activity. Involved in protein O-linked mannosylation. Acts upstream of or within protein glycosylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; lens; mesoderm; pronephros; and shield. Orthologous to human LARGE2 (LARGE xylosyl- and glucuronyltransferase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from Moore et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Moore et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With large2 Human Ortholog
No data available
Associated With large2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002495 Glycosyl transferase, family 8
Homologous_superfamily IPR029044 Nucleotide-diphospho-sugar transferases
Domain Details Per Protein
Protein Length Glycosyl transferase, family 8 Nucleotide-diphospho-sugar transferases
UniProtKB:B3DFN1 750
UniProtKB:Q66PG1 750
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations